In the period from 07.06 – 13.06.2019, a total of 70 cases of measles were reported. From the total number of newly reported cases, 11 cases are from Skopje, while the remaining 59 are from 8 other cities in N. Macedonia –Tetovo (16), Struga (10), Gostivar (9), Veles(8), Kumanovo (7), Stip (5), Ohrid (3) and Valandovo (1).

During this week, the highest number of cases (33) are over the age of 30,

According to the vaccine status, 55 or 78.6% of the registered cases are unvaccinated, incomplete vaccinated or with unknown vaccine status.

In total, since the onset of the epidemic in December 2018 as of June 13, 2019, 1891 cases of measles have been registered in the Republic of North Macedonia with a disease rate of 91.4 per 100,000 inhabitants. Due to the epidemiological criteria, a measles epidemic has been declared on the entire territory of the Republic of North Macedonia.

According to the place of permanent living, measles cases are registered in 24 towns, of which 989 cases are from Skopje, Kumanovo – 221, Tetovo – 194, Struga – 136, Kicevo – 64, Veles – 54, Gostivar – 63, Ohrid-30, Gevgelija -19, Debar -30, Prilep-12, Stip-41, and in other cities less than 10 cases were registered (Chart 1). The highest incidece is registered in Skopje (160.1/100 000, Struga (200.4/100 000, Kumanovo 154.9/100 000) Chart 1.

Chart 1. Geographic distribution of measles in N. Macedonia, December 2018 – June 2019 (n=1891)

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The largest number of cases are from the age group over 30 years -861 (67.6%), and the overall disease rate in this age group is 61.8 per 100,000 inhabitants. 312 (16.5%)children under the age of one year were registered and a disease rate of 1215.1 per 100,000 inhabitants. Children aged 1-4 years are registered with 263 cases (13.9%) and the second highest incidence of 283.3 per 100,000 inhabitants (Chart 2).

Chart 2. Distribution of measles patients in N.Macedonia by age, December 2018-June 2019 (n = 1891)

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According to the vaccine status, 1420 or 86.7% of diseased people are unvaccinated, incompletely vaccinated or with unknown vaccine status. From the non-vaccinated persons, 312 (22%) are under the age of 12 months and are not subject to vaccination, according to the Immunization Calendar.

Out of 263 children aged 1-4 years, 86.7% were unvaccinated or with unknown vaccine status, and from 861 patients over 30 years of age, 74.1% were unvaccinated, incomplete vaccinated or with unknown vaccine status.

 

From the reported cases, 797 or 42.2% were hospitalized, and 281 (14.9%) had complications. Of these, the highest number of complications – 124 or 44.1% were in children from 0-4 –   74 (26.3%) under the age of one year and 50 (17.8%) in children aged 1-4 years, suggesting that this age group is the most affected and susceptible to complications.

In Skopje from the beginning of the epidemic, a total of 15250 children were vaccinated to 14 years of age.

In the rest of the country, a total of 14607 children

The total number of immunized people aged 14 years with MRP vaccine since the start of the epidemic in the republic is 29857.

From the beginning of the epidemic to present date, in the Centers for Public Health, a total of 5115 people have been vaccinated, of which more than 60% are health workers, students and pupils in secondary medical schools, the rest are 2439 contacts and persons over 14 years of age.