During the 10th week of 2018 (05.03.2018 – 11.03.2018), the Republic of Macedonia registered 1980  influenza cases/flu-like diseases(I=91.3/100.000).

Compared with the number of registered cases in the last week, are decreased for 32%(chart 1)and increased for 13 times compared with the cases of the last season.

Chart 1. Distribution of cases of seasonal influenza by week, typical epidemic curve of the seasons 2010-2017, 2016/2017 and 2017/2018

граф 1

Regarding the distribution of patients by age groups, the largest number of cases this week have been reported in the age group of 15-64 years (1209 cases) and the highest incidence is registered in the age group, from 5-14 years. (I=137.8/100.000)

This week the biggest number of influenza cases is registered in Skopje, n= 355 and also, the highest incidence is registered in Sveti Nikole (I = 550.9/ 100.000).

From 31 reporting units, Sveti Nikole, and Kavadarci registered very high activity of the influenza virus, other units- registered low to medium activity,3 units didn’t registered ant cases

Chart 2. Level of influenza activity according to the incidence of 100,000 inhabitants, week 10 2018

grip 10 nedela kartogram

In the 2017/2018 season, the total number of influenza like illness (ILI) cases is 21100 (I = 1019.7/ 100.000).Compared with the previous season (34625 cases), the number has decreased for 39%.

This season the biggest number of influenza cases is registered in Gostivar-2169, Skopje-2741, Strumica-1914, with the highest incindence in Kavadarci (I=3288.1 /100 000).

Regarding the distribution of patients by age groups, the largest number of cases this season have been reported in the age group of 15-64 years, 12767 cases (60.5%) and the highest incidence is registered in the age group of 5-14 years. (I=1888.1/100 000).

 The analysis of the number of seasonal flu cases per month indicates a gradual increase in the number of patients in January (2,396 patients or 11.4%) and a peak in February (12,951 or 61.4%). In march, for 2 weeks are registered 4671 or 22.1%

During this week the laboratory for virology of IPH has received 48 samples, materials for laboratory diagnostics. 29 samples(60.4%) are positive for the presence of influenza virus, subtyped as 65.5% Influenza B (47.4% Yamagata, 21% Victoria and 31.6% are non-subtyped) and 34.5% Influenza A (of which 100% are A(H1N1)pdm09 (chart 2)

Since the beginning of the season 2017/2018, the laboratory received 412 materials, of which, 209 are positive (50.7%) for the presence of the influenza virus, 68.4% are Influenza B (90.2% Yamagata, 4.2% Victoria and 5.6% non-subtyped), and 31.6% are Influenza A of which (78.8% are А(H1N1)pdm09 –and 21.2% Influenza A non-subtyped),

Chart 2. Weekly distribution of number and percentage of positive samples of influenza 2017/2018

граф 2

Vaccination with the seasonal flu vaccine started from October 17, 2017. The total number of 3-type vaccines (Influvac, produced in Abbot Biologicals Olst, Netherlands) for this season is 27997 doses.  According to reports received by CPH / RO, 27997 people were vaccinated, or 100% of total purchased vaccines. The majority of the vaccinated are aged over 65 years – 60.5%, From the total number of the vaccinated  75.2% have a history of chronic diseases.

 

EUROPE

According to records presented in Flu News Europe, the activity of influenza virus in Europe is widespread, The situation is common for this time of year.

This week, 49% samples were confirmed as positive, Influenza А (39%) and Influenza B (61%).

So far, influenza type A is predominant with 34%, and most of the viruses are subtyped as А (H1N1)pdm09 with 65% and  influenza type B with 66% (97% – B/Yamagata).

B / Yamagata type is dominated by the registered Influenza B viruses, but this type is not included in the trivalent vaccine for this season.

Based on the data provided to EuroMOMO, mortality has increased over the past weeks, especially in the countries of the southwestern part from Europe.